BIOLOGIYA MORYA, 2010, Vol. 36, No. 3, pp. 215-220

An extract from the brown alga Laminaria japonica - a promising stress-protective preparation

© 2010 N. F. Kushnerova¹, S. E. Fomenko¹, V. G. Sprygin¹, T. V. Kushnerova², Yu. S. Khotimchenko², E. V. Kondratyeva³, L. A. Drugova¹

¹V.I. Ilyichev Pacific Oceanological Institute, Far East Branch, Russian Academy of Sciences, Vladivostok 690041;
²A.V. Zhirmunsky Institute of Marine Biology, Far East Branch, Russian Academy of Sciences, Vladivostok 690041;
³Vladivostok State Medical University, Vladivostok 690002

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Stress in rats was shown to be accompanied by a decrease in osmotic resistance and antioxidant protection of erythrocytes and an increase in their volume and diameter; cholesterol ethers were reduced, amounts of malone dialdehyde, cholesterol, sphingomyelin, and phospholipids lysofractions were increased. Comparative data on the membrane protecting activity of extracts of Laminaria japonica and Eleutherococcus are presented. The administration of extracts caused the normalization of the parameters of erythrocytes in rats.

Key words: Laminaria japonica, Eleutherococcus, stress, erythrocytes, lipids.